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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VCL All Species: 20.91
Human Site: S380 Identified Species: 46
UniProt: P18206 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.2
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P18206 NP_003364.1 1134 123799 S380 K L E A M T N S K Q S I A K K
Chimpanzee Pan troglodytes XP_001147193 1046 114802 S360 K L E A M T N S K Q S I A K K
Rhesus Macaque Macaca mulatta XP_001118118 547 59720
Dog Lupus familis XP_536395 799 87306 S216 N F T V E K M S A E I N E I I
Cat Felis silvestris
Mouse Mus musculus Q64727 1066 116699 S380 K L E A M T N S K Q S I A K K
Rat Rattus norvegicus P85972 1066 116597 S380 K L E A M T N S K Q S I A K K
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507189 734 80358 E150 G E L C A G K E R R E I L G T
Chicken Gallus gallus P12003 1135 124542 S380 K L E A M T N S K Q A I A K K
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001122153 1131 124026 A381 K L E A L T N A K Q A I A K R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster O46037 961 106284 E361 G I R D R M G E L K S L V H Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans P19826 1010 111904 S363 R L K D L V G S Q N S S G L M
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.1 47.7 63.4 N.A. 93.3 93 N.A. 62.5 93.2 N.A. 85.5 N.A. 42.1 N.A. 39.6 N.A.
Protein Similarity: 100 90.9 47.8 66.5 N.A. 93.9 93.5 N.A. 63.8 96.6 N.A. 93 N.A. 57.7 N.A. 56.7 N.A.
P-Site Identity: 100 100 0 6.6 N.A. 100 100 N.A. 6.6 93.3 N.A. 73.3 N.A. 6.6 N.A. 20 N.A.
P-Site Similarity: 100 100 0 13.3 N.A. 100 100 N.A. 20 100 N.A. 100 N.A. 33.3 N.A. 46.6 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 55 10 0 0 10 10 0 19 0 55 0 0 % A
% Cys: 0 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 19 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 55 0 10 0 0 19 0 10 10 0 10 0 0 % E
% Phe: 0 10 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 19 0 0 0 0 10 19 0 0 0 0 0 10 10 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % H
% Ile: 0 10 0 0 0 0 0 0 0 0 10 64 0 10 10 % I
% Lys: 55 0 10 0 0 10 10 0 55 10 0 0 0 55 46 % K
% Leu: 0 64 10 0 19 0 0 0 10 0 0 10 10 10 0 % L
% Met: 0 0 0 0 46 10 10 0 0 0 0 0 0 0 10 % M
% Asn: 10 0 0 0 0 0 55 0 0 10 0 10 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 0 10 55 0 0 0 0 10 % Q
% Arg: 10 0 10 0 10 0 0 0 10 10 0 0 0 0 10 % R
% Ser: 0 0 0 0 0 0 0 64 0 0 55 10 0 0 0 % S
% Thr: 0 0 10 0 0 55 0 0 0 0 0 0 0 0 10 % T
% Val: 0 0 0 10 0 10 0 0 0 0 0 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _